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Registros recuperados: 193 | |
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Catherine Villard; Annie Andrieux. |
Neuronal differentiation is under the tight control of biochemical and physical information arising from micro-environment. Here, through a panel of poly-L-lysine micropatterns, we wished to assay how external geometrical constraints of neurons may modulate axonal polarization. Constraints applied to either the cell body or to the neurite directions revealed the existence of a differential mechanical tension between the nascent axon and other neurites. Also, we show that centrosome location is not predictive of axonal polarization but responds to the force exerted by the nascent axon. Using curved trajectories for neurite growth inhibited axonal differentiation and prevented formation of multiple axons normally induced by cytochalasin or taxol treatments.... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Neuroscience. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/6021/version/1 |
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Leonardo Varuzza; Arthur Gruber; Carlos A. B. Pereira. |
Most of the statistical tests currently used to detect differentially expressed genes are based on asymptotic results, and perform poorly for low expression tags. Another problem is the common use of a single canonical cutoff for the significance level (p-value) of all the tags, without taking into consideration the type II error and the highly variable character of the sample size of the tags.

 This work reports the development of two significance tests for the comparison of digital expression profiles, based on frequentist and Bayesian points of view, respectively. Both tests are exact, and do not use any asymptotic considerations, thus producing more correct results for low frequency tags than the chi-square test. The... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Bioinformatics. |
Ano: 2008 |
URL: http://precedings.nature.com/documents/2002/version/2 |
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Michael J. Quinn; Mary Ann Ottinger. |
The "silence" in Rachel Carson's Silent Spring1 alludes to the demise of bird populations through reproductive problems and death resulting from exposure to the pesticides of that time, many of which are endocrine active. Endocrine disrupting chemicals (EDCs) are compounds which may interfere with the endocrine system, producing effects that may disrupt the physiologic function of hormones. Early research on EDC exposure in humans and wildlife has focused mainly on reproductive effects of estrogenic chemicals, however recent studies have revealed that effects of estrogenic as well as non-estrogen active chemicals are often more far reaching than the reproductive system, and even mild exposures experienced early in development may... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Ecology; Earth & Environment. |
Ano: 2008 |
URL: http://precedings.nature.com/documents/1492/version/1 |
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I. C. Baianu. |
This novel Soybean Composition Database from the AFC-NMR & NIR Spectroscopy Facility of the College of ACES at the University of Illinois at Urbana includes more than 12,000 NIR measurements on soybeans from the International Soybean Germplasm Collection, such as those received from Peking at the National Soybean Collection.
Excel files (.xls) of our novel spectroscopic data are currently available for all 80,000 + NIR and FT-NMR measurements; such data are made available from an ultra-fast and secure supercomputer server utilizing the current version of the Scientific-Linux OS-based software. 

A detailed account is also presented of our high-resolution nuclear magnetic resonance (HR-NMR) and... |
Tipo: Manuscript |
Palavras-chave: Biotechnology; Chemistry; Developmental Biology; Genetics & Genomics; Molecular Cell Biology; Bioinformatics; Plant Biology. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/6201/version/1 |
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Guenther Witzany. |
Telomeres identify natural chromosome ends being different from broken DNA through differences in their "molecular syntax" (M.Eigen) which determines the functions of reverse transcriptase and its integrated RNA template, telomerase. Although telomeres play a crucial role in the linear chromosome organization of eukaryotic cells, their molecular syntax descended from an ancient retroviral competence. This is an indicator for the early retroviral colonization of large double stranded DNA viruses, which are putative ancestors of the eukaryotic nucleus.
This talk will demonstrate certain advantages of the biosemiotic approach towards our evolutionary understanding of telomeres: focus on the genetic/genomic structures as... |
Tipo: Poster |
Palavras-chave: Developmental Biology; Ecology; Genetics & Genomics; Microbiology. |
Ano: 2007 |
URL: http://precedings.nature.com/documents/932/version/1 |
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Ruud F. R. van der Weel; Audrey van der Meer. |
A fundamental property of most animals is the ability to see whether an object is approaching on a direct collision course and, if so, when it will collide. Using high-density electroencephalography in 5- to 11-month-old infants and a looming stimulus approaching under three different accelerations, we investigated how the young human nervous system extracts and processes information for impending collision. Here we show that infants' looming related brain activity is characterized by theta oscillations. Source analyses reveal clear localised activity in the visual cortex. Analysing the temporal dynamics of the source waveform, we provide evidence that the temporal structure of different looming stimuli is sustained during processing in the more... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Neuroscience. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/2917/version/1 |
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Rodrick Wallace. |
For the broad spectrum of cognitive biological phenomena having 'dual' information sources, isolation from crosstalk between them requires more metabolic free energy than permitting correlation. This allows an evolutionary exaptation leading to dynamic global broadcasts at multiple scales, similar to the well-studied exaptation of noise to trigger stochastic resonance amplification in physiological systems. Entropy gradient models adapted from nonequilibrium thermodynamics lead to an index theorem in which analytic solutions of empirical equations describe different possible topological modes. Not only is the living state characterized by cognition at every scale and level of organization, but by multiple, shifting, tunable, cooperative... |
Tipo: Manuscript |
Palavras-chave: Biotechnology; Developmental Biology; Ecology; Immunology; Molecular Cell Biology; Neuroscience; Pharmacology; Evolutionary Biology. |
Ano: 2012 |
URL: http://precedings.nature.com/documents/6898/version/2 |
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Julio Gil; Rafael Lahoz-Beltra; Miguel Gimeno; Jesús Laborda; Javier Nubiala. |
Beauty is a characteristic of objects that provides a perceptual experience of pleasure. In nature, aesthetic appreciation thereof has given rise to the mathematical search for good series (e.g. the Fibonacci series) and proportions (e.g. the Golden proportion) as important elements of beauty. In 1928 the mathematician George David Birkhoff introduced a formula for aesthetic measurement of an object. Birkhoff equation defines the aesthetic value as the amount of order divided by the complexity of the product. These two features can be measured easily in poetry, music, painting, architecture, etc. In the fine arts, it is the artist who manipulates both these features, but how does nature manage order and complexity in living organisms or their parts? Here... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/2976/version/1 |
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Rodrick Wallace. |
We extend a cognitive paradigm for gene expression to the epigenetic epidemiology of mental disorders, recognizing the fundamental role that culture plays in human biology as another heritage mechanism parallel to, and interacting with, the more familiar genetic and epigenetic systems. In the mathematical model, culture acts as another tunable epigenetic catalyst that both directs developmental trajectories and becomes convoluted with individual ontology via a mutually interacting crosstalk mediated by a social interaction that is itself culturally driven. We call for the incorporation of embedding culture as an essential component of the epigenetic regulation of human mental development and its dysfunctions, bringing what is perhaps the central reality of... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Genetics & Genomics; Neuroscience. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3894/version/1 |
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Rodrick Wallace. |
We extend a cognitive paradigm for gene expression to the epigenetic epidemiology of mental disorders, recognizing the fundamental role that culture plays in human biology as another heritage mechanism parallel to, and interacting with, the more familiar genetic and epigenetic systems. In the mathematical model, culture acts as another tunable epigenetic catalyst that both directs developmental trajectories and becomes convoluted with individual ontology via a mutually interacting crosstalk mediated by a social interaction that is itself culturally driven. We call for the incorporation of embedding culture as an essential component of the epigenetic regulation of human mental development and its dysfunctions, bringing what is perhaps the central reality of... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Genetics & Genomics; Neuroscience. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3894/version/2 |
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Mitsugu Inoue; Kazuyo Tsugita. |
Background: The assumption of an invariant fat-free or lipid-free composition is prerequisite for most methods of the estimation of body composition in mammals including human but has not been theoretically demonstrated.
Objective: To demonstrate theoretically and practically the invariant lipid-free composition and to understand the mechanism varying the main components of muscle and adipose tissue which have intimate relationships to lipid accumulation or obesity in mammals. 
Design: Whether the combinations of correlations among energy and main components in the hypothetical lipid-ratio variation model (L-varied model), which reflects the invariant lipid-free composition, are consistent with those in the practical... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3832/version/1 |
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Ahmim Mourad; Moali Aissa. |
Many bats of the Rhinolophidae family are currently threatened all over the world. In Algeria they are represented by six species listed in the IUCN red list and whose hunting habits and diet are, at best, poorly known. This paper describes the diet composition of four of these species (Rhinolophus ferrumequinum, R. hipposideros, R. euryale and R. blasii) in the Bejaia and Jijel districts, and in Kabylia of the Babors region, in northern Algeria. Between March 2007 and January 2008 guano was sampled every fortnight in the different sites used by the species and preys remains identified under microscope. Results show that these Algerian Rhinolophidae prey on three groups of Arthropodes (Insects, Chilopodes and Spiders) whose frequencies vary from one... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Ecology. |
Ano: 2012 |
URL: http://precedings.nature.com/documents/6822/version/1 |
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Registros recuperados: 193 | |
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